OFICIAL Boston Scientific News Gadgets · Apr 30, 2026

What is colorectal cancer, and how is it treated?

In brief · 4 sentences
Based on Boston Scientific News · Apr 30, 2026

Colorectal cancer rates are rising among younger adults, with liver metastases affecting over half of U.S. cases annually. New therapies like Hepatic Artery Infusion and TheraSphere are expanding treatment options for metastatic disease.

What is colorectal cancer, and how is it treated?
Boston Scientific News — Boston Scientific
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Main topic: what is colorectal cancer, and how is it treated?.
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Category affected: gadgets and hardware.
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Figures mentioned: 50, 150,000, 1998.
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Colorectal cancer originates in the colon or rectum, often without early symptoms, and has become the third most common cancer globally. Recent trends show a sharp increase in diagnoses among people under 50, though the causes remain unclear. Possible contributing factors include obesity, diets high in processed foods, and environmental exposures. Symptoms, when present, may resemble common digestive issues, delaying detection.

More than half of the 150,000 annual U.S. colorectal cancer cases involve liver metastases, a condition historically associated with poor prognosis. Advances in oncology have shifted perspectives, with some stage 4 patients now achieving long-term survival through aggressive treatments. Surgical resection remains the primary approach, but only 15% to 20% of patients qualify initially.

Hepatic Artery Infusion (HAI) therapy offers an alternative for unresectable liver tumors by delivering chemotherapy directly to the liver at 400 times the concentration of systemic methods. A surgically implanted pump circulates the drug via the hepatic artery, minimizing systemic side effects. HAI can target undetectable cancer cells, reducing recurrence risk when used alongside surgery.

TheraSphere, another liver-directed therapy, uses Y-90 isotope glass beads to deliver targeted radiation with minimal impact on healthy tissue. Approved in Europe for colorectal liver metastases and in the U.S. for hepatocellular carcinoma, it represents a less invasive option than traditional radiation. Experts note a growing shift from terminal diagnoses to chronic management for stage 4 colorectal cancer.

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